Recent consultations NPPG has responded to as of July 2026

Thank you to our committee members and our specialist interest groups for the comments received on recent consultations.

Since the previous full committee meeting the following consultations have been reviewed:

Consultations

Thank you to our committee members and our specialist interest groups for the comments received on recent consultations and to those who have volunteered to be nominated experts. The following consultations have been reviewed since the September committee meeting:

 

1.              NICE STA
Invitation to participate
Donidalorsen for preventing recurrent attacks of hereditary angioedema in people 12 years and over [ID6457] 28/08/2025 Expert nomination – 30/10/2025
Organisation submission – 30/10/2025
Circulated to committee members 01/09/2025 No comments received. A ‘No comment’ response submitted – 05/11/2025
2.              NICE STA
Draft Scope Consultation
Nerandomilast for treating idiopathic pulmonary fibrosis or progressive pulmonary fibrosis ID6446 03/09/2025 Deadline for comments – 01/10/2025 Circulated to committee members 03/09/2025 No comments received. A ‘No comment’ response submitted. 01/10/2025
3.              NICE STA
Draft Scope Consultation
Orforglipron for managing overweight and obesity ID6516 04/09/2025 Deadline for comments – 02/10/2025 Circulated to committee members 04/09/2025 No comments received. A ‘No comment’ response submitted. 02/10/2025
4.              NICE STA
Invitation to participate
Brensocatib for treating non-cystic fibrosis bronchiectasis in people 12 years and over [ID6448] 02/10/2025 Deadline for comments 04/12/2025 Circulated to committee members 03/10/2025 Submitted comments – 04/12/2025
5.              NICE STA
Draft Scope Consultation
Obicetrapib and obicetrapib–ezetimibe for treating primary hypercholesterolaemia or mixed dyslipidaemia ID6519 04/11/2025 Deadline for comments 02/12/2025 Circulated to committee members 04/11/2025 No comments received. A ‘No comment’ response submitted 02/12/2025
6.              NICE STA
Invitation to participate
Betula verrucosa (Itulazax 12 SQ-Bet) for treating moderate to severe allergic rhinitis, conjunctivitis, or both, caused by tree pollen in people 5 to 17 years [ID6537] 04/11/2025 Deadline for expert nominations and comments is 20/01/2026 Circulated to committee members 04/11/2025 No comments received. A ‘No comment’ response submitted 20/01/2026
7.              NICE STA
Invitation to participate
Semaglutide for treating moderate to advanced liver fibrosis (without cirrhosis) caused by metabolic dysfunction-associated steatohepatitis [ID6458] 04/11/2025 Deadline for expert nominations and comments is 20/01/2026 Circulated to committee members 05/11/2025 No comments received. A ‘No comment’ response submitted 20/01/2026
8.              NICE STA
invitation to participate
12 SQ-HDM SLIT for treating allergic rhinitis caused by house dust mites in children 5 to 11 years [ID6510] 04/11/2025 Deadline for expert nominations and comments is 20/01/2026 Circulated to committee members 05/11/2025 No comments received. A ‘No comment’ response submitted 20/01/2026
9.              NHS England Highly Specialised Services Mobile Extracorporeal Membrane Oxygenation (ECMO) for Neonates, Infants & Children 03/11/2025 Deadline for feedback 02/12/2025 Circulated to committee members and Sandra Forbes at Profile – 05/11/2025
10.           NICE STA
Invitation to participate
Onasemnogene abeparvovec (intrathecal) [ID6556] 24/11/2025 Deadline for expert nominations and organisation submission is 09/02/2026 Circulated to committee members – 24/11/2025 Expert nomination form and Appendix B for Satvinder Mahal submitted by PR on 06/01/2026
11.           NICE STA
Invitation to participate
Myopia (3-14 years) – atropine (low dose, eye drops) [ID6517] 26/11/2025 Deadline for expert nominations and organisation submission is 09/02/2026 Circulated to committee members – 26/11/2025 No comments received. A ‘No comment’ response submitted – 09/02/2026
12.           NICE STA
Invitation to participate
Orforglipron for managing overweight and obesity [ID6516] 01/02/2025 Deadline for expert nominations and organisation submission is 16/02/2026 Circulated to committee members – 02/12/2025 Submitted comments received from Jo Crook – 10/02/2026
13.           NICE HTE
Draft Scope Consultation
Setmelanotide for treating obesity and hyperphagia in Bardet-Biedl syndrome (review of HST31) [ID6598] 01/12/2025 Deadline for comments 15/12/2025 Circulated to committee members – 02/12/2025 No comments received. A ‘No comment’ response submitted 15/12/2025
14.           NICE STA
Invitation to participate
Nerandomilast for treating idiopathic pulmonary fibrosis or progressive pulmonary fibrosis [ID6446] 05/12/2025 Deadline for expert nominations and organisation submission is 20/02/2026 Circulated to committee members – 08/12/2025 No comments received. A ‘No comment’ response submitted – 20/02/2026
15.           NICE STA
Draft Scope Consultation
Denecimig (Mim8) for preventing bleeding episodes in haemophilia A in people 1 year and over ID6400 10/12/2025 Deadline for comments 15/01/2026 Circulated to committee members – 10/12/2025 No comments received. A ‘No comment’ response submitted 15/01/2026.
16.           NHS England Highly Specialised Services High Consequence Infectious Diseases (HCID) Critical Care Transfer Services 10/12/2025 Deadline for feedback 09/01/2026 Circulated to committee members – 11/12/2025
17.           NICE STA
Draft Scope Consultation
Setmelanotide for treating acquired hypothalamic obesity in people 4 years and over ID6542 11/12/2025 Deadline for comments 16/01/2026 Circulated to committee members – 11/12/2025 Submitted comments received from Nabil Boulos- 16/01/2026
18.           NICE Highly Specialised Technology
Invitation to participate
Setmelanotide for treating obesity and hyperphagia in syndrome (review of HST31) [ID6598] 18/12/2025 Deadline for expert nominations and organisation submission is 11/02/2026 Circulated to committee members – 19/12/2025
19.           NICE STA
Invitation to participate
Obicetrapib and obicetrapib–ezetimibe for treating primary hypercholesterolaemia or mixed dyslipidaemia [ID6519] 05/01/2026 Deadline for expert nomination and comments – 09/03/2026 Circulated to committee members – 06/01/2026
20.           NICE STA
Draft Scope Consultation
Apadamtase alfa for treating congenital thrombotic thrombocytopenic purpura caused by ADAMTS-13 deficiency ID6192 21/01/2026 Deadline for comments – 18/02/2026 Circulated to committee members – 21/01/2026
21.           NICE STA
Draft guidance document
Polihexanide 0.8 mg/ml eye drops for treating acanthamoeba keratitis in people 12 years and over [ID6497] 06/02/2026 Deadline for comments – 06/03/2026 Circulated to committee members – 10/02/2026
22.           NICE Draft Guideline Draft guideline on Neonatal infection: antibiotics for prevention and treatment – 19/02/2026 to 04/03/2026 19/02/2026 Deadline for comments 04/03/2026 Circulated to committee members – 26/02/2026
23.           NICE STA
Draft Scope Consultation
Scoping Workshop and Consultation Invitation (All C&C): Mucopolysaccharidosis (type IIIA) – rebisufligene etisparvovec ID6540 04/03/2026 Deadline for comments – 01/04/2026 Circulated to committee members – 04/03/2026
24.           NICE STA
Invitation to participate
Denecimig (Mim8) for preventing bleeding episodes in haemophilia A in people of any age [ID6400] 09/03/2026 Deadline for expert nomination and comments – 19/05/2026 Circulated to committee members – 09/03/2026
25.           NICE STA
Draft Scope Consultation
Leriglitazone for treating cerebral adrenoleukodystrophy in boys and men 2 years and over [ID3903] 27/03/2026 Deadline for comments 28/04/2026 Circulated to committee members – 27/03/2026
26.           NICE STA
Draft Scope Consultation
Sirolimus gel for treating facial angiofibroma from tuberous sclerosis complex in people 6 years and older (review of TA972) [ID6757] 06/05/2026 Deadline for comments 27/05/2026 Circulated to committee members – 06/05/2026
27.           NICE HST
Invitation to participate
Leriglitazone for treating cerebral adrenoleukodystrophy in people 2 and over [ID3903] 20/05/2026 Deadline for expert nomination and comments – 16/07/2026 Circulated to committee members – 21/05/2026
28.           NICE STA
Draft Scope Consultation
Semaglutide 7.2 mg dose for managing obesity ID6699 28/05/2026 Deadline for comments 25/06/2026 Circulated to committee members – 01/06/2026
29.           PrescQipp Registered for 2026-28 work plan stakeholder consultation 30/04/2026 Circulated to committee members and collated responses
30.           NICE STA
Invitation to participate
Sirolimus gel for treating facial angiofibroma from tuberous sclerosis complex in people 6 years and older (review of TA972) [ID6757] 10/06/2026 Deadline for expert nomination and comments – 12/08/2026 Circulated to committee members – 10/06/2026 Expert nomination for Kalindi Rajani submitted on 23 Jun 2026 – 9:07 by NPPG Information Officer

CCA – Cost Comparison Appraisal; STA – Single Technology Appraisal; QSU – Quality Standard Update; SpecComm – Specialised Commissioning; MTA – Multiple Technology Appraisal; HTSE – Highly Specialised Technologies Evaluation.